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目的探讨嘉兴市常见恶性肿瘤的危险因素,为进行全市肿瘤预防控制提供依据。方法收集肺癌、胃癌、肝癌、大肠癌(结、直肠癌)、食管癌、乳腺癌等6种常见原发恶性肿瘤600例,采用1∶2配对的病例对照研究,采用单因素及多因素logistic回归模型进行拟合,筛选嘉兴市常见恶性肿瘤的主要危险因素。结果做饭时眼睛或咽喉感觉受到烟雾刺激(OR=1.37)、十年前居住地500m内周围有工厂(OR=1.82)、被动吸烟(OR=1.24)、肺结核病史(OR=3.04)、血吸虫病史(OR=3.33)、肝病和肝硬化病史(OR=5.12)、其他下消化系疾病病史(OR=16.80)和直系亲属肿瘤史(OR=1.53)为恶性肿瘤发病的危险因素,自我调节强,易适应环境(OR=0.52)、近些年无较大的精神创伤(OR=0.63)为保护因素。结论做饭时眼睛或咽喉感觉受到烟雾刺激、十年前居住地500m内周围有工厂、被动吸烟、肺结核病史、血吸虫病史、肝病和肝硬化病史、其他下消化系疾病病史和直系亲属肿瘤史为嘉兴市常见恶性肿瘤发病的共同危险因素,自我调节强易适应环境、近些年无较大的精神创伤为保护因素。
Objective To explore the risk factors of common malignant tumors in Jiaxing City and provide the basis for the prevention and control of cancer in the city. Methods Sixty-six primary malignant tumors including lung cancer, gastric cancer, liver cancer, colorectal cancer (colorectal cancer), esophageal cancer and breast cancer were collected. A case-control study with 1: 2 matching was used. Regression model fitting, screening of Jiaxing common malignant tumor of the main risk factors. (OR = 1.37), passive smoking (OR = 1.24), history of pulmonary tuberculosis (OR = 3.04), schistosomiasis (OR = 3.33), history of liver disease and cirrhosis (OR = 5.12), history of other lower digestive diseases (OR = 16.80) and history of immediate family members (OR = 1.53) were risk factors of malignant tumor. , Easy to adapt to the environment (OR = 0.52), in recent years no major trauma (OR = 0.63) as a protective factor. Conclusion The eyes or throat felt smoke-stimulated during cooking. There was a factory around 500m within ten years ago, passive smoking, history of pulmonary tuberculosis, history of schistosomiasis, history of liver disease and cirrhosis, history of other lower gastrointestinal diseases and history of immediate relatives The common risk factors of common malignant tumor in Jiaxing City are self-regulating and adaptable to the environment. In recent years, there is no major trauma as a protective factor.