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本文检测30例慢性肺心病患者外周血NK细胞活性,并探讨重组人IL-2、IFN-γ在体外对患者NK细胞活性的影响。结果发现肺心病患者NK细胞活性明显低于正常对照组(p<0.01),且在急性加重期NK细胞活性下降更为显著,IL-2、IFN-γ在体外能明显提高肺心病患者的NK细胞活性。
In this paper, 30 cases of chronic pulmonary heart disease patients with peripheral NK cell activity, and explore the recombinant human IL-2, IFN-γ in vitro NK cell activity. The results showed that the activity of NK cells in patients with cor pulmonale was significantly lower than that in the normal control group (p <0.01), and the activity of NK cells in acute exacerbation was more significant. IL-2 and IFN-γ significantly increased the NK Cell activity.