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目的探讨法莫替丁与西咪替丁治疗消化性溃疡的临床疗效。方法选取我院2015年1月-2016年10月收治的消化性溃疡患者80例,分两组各40例,分别为法莫替丁组和西咪替丁组,对两组临床治疗的方法疗效进行分析。结果法莫替丁组经临床治疗,治愈34例(85%)、明显好转6例(15%),总有效率100%;西咪替丁组治愈25例(62.5%)、明显好转13例(32.5%)、无效2例(5%),总有效率95%。临床疗效法莫替丁明显优于西咪替丁组。结论法莫替丁与西咪替丁相比,药效持续时间长,口服吸收良好,生物利用度高,副作用少,有临床推广价值。
Objective To investigate the clinical efficacy of famotidine and cimetidine in the treatment of peptic ulcer. Methods Eighty patients with peptic ulcer admitted to our hospital from January 2015 to October 2016 were enrolled in this study. Forty patients in two groups were treated with famotidine and cimetidine respectively. The clinical treatment of the two groups Efficacy analysis. Results In the famotidine group, 34 cases (85%) were cured and 6 cases (15%) were cured. The total effective rate was 100%. Cimetidine group was cured in 25 cases (62.5%) and obviously improved in 13 cases (32.5%), invalid in 2 cases (5%), the total efficiency of 95%. Clinical efficacy of famotidine was significantly better than cimetidine group. Conclusion Famotidine and cimetidine compared to long duration of efficacy, good oral absorption, high bioavailability, fewer side effects, the clinical value of the promotion.