目的探讨小儿狼疮性肾炎（ＬＮ）的临床特点。方法对８８例小儿ＬＮ和２００例成人ＬＮ进行了比较分析。结果小儿组男性比例较高，初发症状以发热、消瘦、乏力、水肿、肺部感染等多见；肾脏受累率两组差异不大，但儿童组受累的严重程度较成人重，且从发病至出现肾脏损害的平均时间较短；小儿贫血、血小板减少较多见，狼疮细胞阳性率高；感染为小儿ＬＮ死亡的主要原因。结论小儿ＬＮ的早期诊治很重要 Objective To investigate the clinical features of pediatric lupus nephritis (LN). Methods 88 cases of pediatric LN and 200 cases of adult LN were compared and analyzed. Results The proportion of males in infants was higher than that in males. The onset symptoms were fever, weight loss, emaciation, edema and lung infection. The incidence of renal involvement was not significantly different between the two groups. However, The average time to renal damage is shorter; anemia in children, thrombocytopenia more common positive rate of lupus cells; infection is the main reason for LN death in children. Conclusion Early diagnosis and treatment of pediatric LN is very important