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目的:评价用131I-SPECT/CT融合显像方法对分化型甲状腺癌(DTC)术后患者是否有转移病灶的临床诊断意义。方法:156例DTC术后患者在随诊的不同阶段行常规核医学全身131I平面显像,对所见的异常摄取灶再进行131I-SPECT/CT融合显像,比较这两种显像方法的诊断符合率、灵敏度及特异性。结果:全身131I平面显像发现DTC术后异常摄取灶的阳性率为57.05%(89/156),其中61例有颈部摄取患者中,131I-SPECT/CT融合显像提高了对该区域复发和转移的诊断符合率、灵敏度和特异性,在其余颈部以外区域有摄取灶的28例患者中,131I-SPECT/CT融合显像亦可对颈部以外区域可疑摄取灶做出准确定位及定性诊断。结论:131I-SPECT/CT融合显像与常规核医学平面显像相比,在对DTC术后患者随访时有更高的诊断价值,对DTC术后患者的诊疗决策亦有重要意义。
Objective: To evaluate the clinical diagnostic value of 131I-SPECT / CT fusion imaging in patients with differentiated thyroid carcinoma (DTC) after operation. Methods: One hundred and sixty-five patients with DTC underwent routine nuclear medicine whole-body 131I planar imaging at different stages of follow-up, and 131I-SPECT / CT fusion imaging was performed on the abnormal focus of the lesions. Diagnostic coincidence rate, sensitivity and specificity. Results: The positive rate of abnormal lesions in patients with DTC was found to be 57.05% (89/156) in 131I plain imaging. Among 131 cases of cervical ingestion, 131I-SPECT / CT fusion enhanced the recurrence of this area And sensitivity, specificity and specificity of metastatic diagnosis. Out of the remaining 28 patients with a focal lesion outside the neck, 131I-SPECT / CT fusion imaging can also accurately locate suspicious lesions outside the neck area and Qualitative diagnosis. Conclusions: 131I-SPECT / CT fusion imaging is more valuable in the follow-up of patients with DTC compared with conventional nuclear imaging. It is also of great significance in the diagnosis and treatment of DTC patients.