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目的探讨辅酶Q10联合果糖二磷酸治疗小儿病毒性心肌炎的疗效。方法选取2011年2-8月湖南省儿童医院收治的病毒性心肌炎患儿54例作为研究对象,将上述患儿随机分成2组,观察组、对照组均为27例,观察组在常规治疗的基础上再联合使用辅酶Q10、果糖二磷酸,对照组仅给予常规治疗,比较两组患者的疗效。结果观察组的治疗效果显著优于对照组,两组比较差异有统计学意义(P<0.05)。治疗2周后,观察组肌酸激酶(CK)、天冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)的降低幅度显著高于对照组,两组比较差异有统计学意义(P<0.01)。结论在常规治疗基础上联合使用辅酶Q10、果糖二磷酸可显著提高小儿病毒性心肌炎的疗效。
Objective To investigate the efficacy of coenzyme Q10 combined with fructose diphosphate in the treatment of viral myocarditis in children. Methods From January to August in 2011, 54 children with viral myocarditis admitted to Children’s Hospital of Hunan Province were selected as the study subjects. The children were randomly divided into two groups. The observation group and the control group were all 27 cases. In the observation group, Based on the combined use of coenzyme Q10, fructose diphosphate, the control group was given only conventional treatment, the efficacy of the two groups were compared. Results The observation group was significantly better than the control group, the difference was statistically significant (P <0.05). After 2 weeks of treatment, the decrease of creatine kinase (CK), aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) in the observation group was significantly higher than that in the control group, with significant difference between the two groups P <0.01). Conclusions The combination of coenzyme Q10 and fructose diphosphate can significantly improve the efficacy of viral myocarditis in children on the basis of routine treatment.