J.Am.Chem.Soc.2017,139,9767～9770联硼化合物作为制备芳基或烷基硼酸酯的重要合成原料被广泛应用于工业中,而利用其还原性在无过渡金属参与下实现碳碳键构建则鲜有报道.利用简便易得的手性联硼酸酯实现高立体选择性的偶联反应将是很有吸引力的有机合成方法.手性双异喹啉既可以作为相转移催化剂,又是重要的手性配体骨架,而现有的手性双异喹啉的合成方 J.Am.Chem.Soc.2017,139,9767 ~ 9770 Bibenzo compounds are widely used in the industry as an important synthetic raw material for the preparation of aryl or alkylboronic esters, and their reducibility is utilized in the absence of transition metal However, there are few reports about the carbon-carbon bond formation.It is an attractive organic synthesis method to use a readily available chiral boronic ester to achieve a highly stereoselective coupling reaction. Phase transfer catalyst, which is an important chiral ligand backbone, while the existing chiral double isoquinoline synthesis side