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我科1994-1995年共收治婴幼儿腹泻100例,其中男52例,女48例;年龄<6个月15例,-12个月65例,-3岁20例;急性腹泻81例,迁延性腹泻19例。临床表现:发热65例,呕吐45例,轻度脱水50例.中度脱水9例,重度脱水1例。大便外观:蛋花汤样或稀糊便92例,脓血便8例。大便镜检:白细胞<10/HP30例。>15/HPl3例,伴有红细胞lO-20/HP8例.脂肪球15例,大便培养9例均为阴性。治疗方法:整肠生O.125/次,<6个月一日2次,-l岁一日3次,>1岁0.25/次,一日2次,首次加倍,服药5-7天。治疗期间不加任何抗生素。疗效判定:显效:3天症状消失,大便<2次/日;有效:5天症状消失,大便<2次/日;无效:7天症状未全消失,大便>3次/日.结果:显效35例,其中包括15例迁延性腹泻;有效52例,无效13例,总有效率为87％。整肠生为地衣芽孢杆菌生态制剂,具有生物“夺氧作用”,造成肠道低氧,促进某些肠道厌氧菌生长,维持肠道的正常微生态环境,进而发挥生物学活力,起到防病治病作用。在治疗中未发现毒副作用。对婴幼儿急性腹泻,特别是长期应用抗生素无效的迁延性腹泻,疗效显著,值得临床应用。
A total of 100 cases of infantile diarrhea were treated in our department from 1994 to 1995, including 52 males and 48 females. Among them, 15 cases were aged <6 months, 65 cases were -12 months and 20 cases were -3 years old. 81 cases were acute diarrhea 19 cases of diarrhea. Clinical manifestations: fever 65 cases, 45 cases of vomiting, mild dehydration in 50. 9 cases of moderate dehydration, severe dehydration in 1 case. Stool appearance: egg-like soup or paste it will be 92 cases, 8 cases of pus and blood. Stool microscopy: white blood cells <10 / HP30 cases. > 15 / HPl3 cases, accompanied by erythrocyte lO-20 / HP8 cases, 15 cases of fat globules, stool culture in 9 cases were negative. Treatment: Intestinal Health O.125 / times, <6 months, 2 times a day, l-year-old three times a day,> 1 year old 0.25 / times, twice a day for the first time doubled, taking 5-7 days. During treatment without any antibiotics. Effectiveness: 3 days symptoms disappear, stool <2 times / day; effective: 5 days symptoms disappear, stool <2 times / day; invalid: 7 days symptoms did not disappear, stool> 3 times / day. 35 cases, including 15 cases of persistent diarrhea; effective in 52 cases, ineffective in 13 cases, the total effective rate was 87%. Whole intestine is Bacillus licheniformis ecological preparation, with biological “role of oxygen”, resulting in intestinal hypoxia, promote the growth of certain intestinal anaerobic bacteria to maintain the normal intestinal microflora, and then play a biological activity, from To prevent and cure diseases. No side effects were found during treatment. For infants and young children with acute diarrhea, especially long-term use of antibiotics ineffective persistent diarrhea, a significant effect, it is worth clinical application.