对我国大陆首次从猪群中分离到的猪型（Ｈ１Ｎ１）流感病毒血凝素（ＨＡ）基因核苷酸全序列进行了测定，其长度为１７７８ｂｐ，共编码５６６个氨基酸，其中信号区１７个，ＨＡ１区３２６个，多肽连接区１个，ＨＡ２区２２２个。与Ａ／ＮＪ／１１／７６（Ｈ１Ｎ１）毒株ＨＡ蛋白分子上氨基酸序列相比，其同源性为９４．５％，而ＨＡ１和ＨＡ２区的同源性分别为９３．６％和９７．７％。同时在ＨＡ１区的第２７６个位点上多１个糖基化点，然而其余的包括２个重叠的糖基化点均相同。 The complete nucleotide sequence of the hemagglutinin (HA) gene of porcine swine influenza virus (H1N1) was isolated from pig herds for the first time in China. The length of the HA gene was 1778bp, encoding a total of 566 amino acids, of which 17 326 in the HA1 region, 1 in the polypeptide linker region and 222 in the HA2 region. Compared with the amino acid sequence of HA protein of A / NJ / 11/76 (H1N1), the homology was 94.5%, while the homologies of HA1 and HA2 were 93.6% and 97, respectively. 7%. At the same time, more glycosylation sites are located at the 276th site in the HA1 region, while the remaining sites including the two overlapping glycosylation sites are the same.