,Did ZIKV evolve to be more dangerous? A new clue towards neurovirulence

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Before 2015,Zika virus (ZIKV) was a little-known flavivirus that caused sporadic symptomatic infections in humans (under 20 reported cases,but likely many more unreported asymptomatic cases)in the decades following its discovery during 1947 in Africa.Infections with ZIKV result in a mild acute illness including a self-resolving fever and rash,and no fatalities have been attributed to acute ZIKV fever.
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