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本文综述和讨论药用辅料对制剂质量影响的有关问题,期望引起制药科技人员对研制、生产、应用和供应新型辅料的关注和兴趣。一、辅料在药剂制备中的作用任何药剂在制备过程中几乎都要选用一些辅料,有时辅料的用量甚至大于主药用量。因此,辅料的性质往往直接决定着制剂的质量。例如:片剂赋形剂的种类和性质就可能直接关系到片剂能否压制成型,成品的外
This article summarizes and discusses the issues related to the influence of pharmaceutical excipients on the quality of pharmaceutical preparations. It is expected that pharmaceutical scientists and technicians will pay attention to the development, production, application and supply of new excipients. First, the role of excipients in the preparation of pharmaceutical agents in the preparation process of any pharmaceutical almost all use some accessories, and sometimes the amount of accessories is even greater than the amount of the main drug. Therefore, the nature of excipients often directly determines the quality of the formulation. For example, the type and nature of tablet excipients may directly relate to whether tablets can be molded or not,