论文部分内容阅读
一、原发性血小板减少性紫癜(ITP):该病系一种由于IgG抗体介导而引起血小板破坏的疾患。对出血症状较重者可首选皮质激素治疗,其升高血小板、防止和控制出血的效果较明显,对急性型疗效尤著,对慢性型常可获得临床缓解。激素治疗ITP的机制是可增加内皮细胞和蛋白质合成,从而增加毛细血管抵抗力,改善出血,并可延长血小板平均寿命。常用药物为强的松,每日1～2毫克/公斤体重,病情危重者可加大剂量或静滴氢化考的松200毫克～300毫克/日,也可用强地松龙静
First, idiopathic thrombocytopenic purpura (ITP): The disease is a disease caused by IgG antibody-mediated destruction of platelets. The more severe symptoms of bleeding may be the first choice of corticosteroid therapy, which increase platelets, to prevent and control the bleeding effect is more obvious, particularly acute type of effect, for chronic type can often get clinical remission. Hormone treatment of ITP mechanism is to increase endothelial cell and protein synthesis, thereby increasing capillary resistance, improve bleeding, and can extend the average life expectancy of platelets. Commonly used drugs for prednisone, daily 1 ~ 2 mg / kg body weight, critically ill patients can increase the dose or intravenous hydrocortisone 200 mg ~ 300 mg / day, can also be used prednisolone static