盐酸二氢埃托菲(Dihydroctorphine,DHE)是阿片受体激动剂类高效镇痛药。1990年由我国研制成功并上市。其镇痛作用是与阿片受体发生立体专一性结合,使其兴奋。剂量与效应关系与吗啡一样呈线性;但药理活性比吗啡强6000～10000倍。镇痛作用强于吗啡,安全系数大。在临床各科的应用也日趋广泛,而不良反应也渐增多,提示临床注意。 Dihydrochloride Hydrochloride (DHE) is an opioid receptor agonist. Developed by China in 1990 and listed. Its analgesic effect is the three-dimensional and opioid receptor-specific binding, making it excited. The dose-response relationship is as linear as morphine; however, its pharmacological activity is 6000 to 10,000 times stronger than morphine. Analgesic effect stronger than morphine, safety factor. In clinical departments of the increasingly wide range of applications, and adverse reactions are also increasing, suggesting clinical attention.