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目的:探讨注射用头孢哌酮钠不良反应的一般规律,为临床安全合理用药提供参考。方法:采用文献回顾性研究方法,对150例头孢哌酮不良反应患者的临床资料进行统计分析和总结。结果:头孢哌酮不良反应类型多,且可能涉及多个器官和系统,其中以变态反应和双硫仑样反应居多。结论:医护人员应当加强对头孢哌酮的用药监护,发生不良反应时要及时做出处理;尤其要叮嘱患者用药前后禁止饮酒,减少不良反应的发生。
Objective: To investigate the general rules of adverse reactions of cefoperazone sodium for injection and to provide reference for clinical safe and rational drug use. Methods: The literature retrospective study of 150 cases of cefoperazone adverse reactions in patients with clinical data were analyzed and summarized. Results: There were many types of cefoperazone adverse reactions, and may involve multiple organs and systems, with the majority of allergic reactions and disulfiram-like reactions. Conclusion: Medical staff should strengthen the monitoring of cefoperazone medication, timely treatment of adverse reactions should be made; in particular, to urge patients to prohibit alcohol consumption before and after treatment to reduce the incidence of adverse reactions.