头孢吡肟是第四代头孢菌素,临床应用广泛。近年来国内有文献报道,本品可致尿毒症患者抗生素脑病,现摘要如下。金晓冰[1]报道:男,37岁,尿毒症患者,因尿路感染给予头孢吡肟1.0 g静脉滴注,2次/d,第3天晚用药后,言语少,语无伦次,情绪低落。停药后行血液透析治疗,2 h后上述症状逐渐 Cefepime is the fourth generation cephalosporin, with wide range of clinical applications. In recent years, there are domestic literature reports, this product can cause antibiotic encephalopathy in patients with uremia, are summarized as follows. Jin Xiaobing [1] reported: male, 37 years old, patients with uremia, urinary tract infection given cefepime 1.0 g intravenous infusion, 2 times / d, after the third day of medication, less verbal, incoherent and depressed. Hemodialysis after stopping treatment, 2 h after the above symptoms gradually