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静脉给予重组的组织型纤溶酶原激活物(rt-PA),在90分钟内约25%病人梗塞区供血冠状动脉不能再通,13~33%的再闭塞率,再灌注损伤,为其不足之处。实验表明前列环素(PGI_2)类似物伊洛前列素(Iloprost)能促进血栓溶解,减轻心肌休克。作者观察两药并用的效果。方法参加实验者为1987年9月24日~1988年3月1日收治的病人,要求胸部不适≥20min 而<6h,两个以上相邻导联上ST 段抬高≥1mm,且在该部位以前无心肌
Intravenous administration of recombinant tissue-type plasminogen activator (rt-PA), coronary artery can not be re-supplied in about 25% of patients within 90 minutes, re-occlusion rate of 13-33%, reperfusion injury, Insufficient. Experiments show that prostacyclin (PGI_2) analog Iloprost can promote thrombolysis, reduce myocardial shock. The author observed the effect of both drugs. Methods The participants who participated in the experiment from September 24, 1987 to March 1, 1988 were required to have chest discomfort ≥20 min and <6 h, ST segment elevation ≥1 mm on two or more adjacent leads, No heart muscle before