陈××、女,一岁八个月,出生一周后发现每遇吮乳时双眼流泪,哭闹时无泪,伴耳聋.于1990年10月30日就诊我院.患儿为二胎、足月剖腹产,无产伤及其它外伤史,母亲孕期末发烧及服药史,父母非近亲结婚.家族中母系无有关病史记载.父系中,其父口吃、反应迟钝、智力轻度障碍,另一姑先天性痴呆、大小便失禁全身瘫软、不能站立走路、双手不能握持东西、两 Chen × ×, female, one year and eight months old, one week after she was born, she found that her tears were crying every time she was sucking milk, she was suffering from deafness when she was crying, and she was admitted to our hospital on October 30, 1990. The second child, Full-term caesarean section, no history of injury and other trauma, the mother had a fever and medication history at the end of pregnancy, parents marry non-relatives .Mother family no history records .Father, father eating, unresponsive, mental retardation, Congenital dementia, incontinence whole body limp, can not stand walking, hands can not hold things, two