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目的探讨急性化脓穿孔性阑尾炎术后切口感染的相关因素。方法回顾性分析2009年1月至2011年6月期间我院普外科手术治疗的化脓穿孔性阑尾炎161例患者的临床资料。结果 161例患者中35例(21.7%)发生了切口感染。单因素分析结果表明,肥胖(体质指数>30 kg/m2)、手术时间超过1 h、术前未预防性应用抗生素及术后首次切口换药时间>3 d者切口感染发生率高(P<0.05);多因素分析结果表明,手术时间超过1 h及术前未预防性应用抗生素是急性化脓穿孔性阑尾炎术后切口感染的独立危险因素(P<0.05)。结论早期诊治、降低手术时间、术前合理预防性应用抗生素有助于减少切口感染机会。
Objective To investigate the related factors of incision infection after acute suppurative perforation appendicitis. Methods The clinical data of 161 patients with purulent perforation appendicitis treated by general surgery in our hospital from January 2009 to June 2011 were retrospectively analyzed. Results Of the 161 patients, 35 (21.7%) incisional wounds occurred. Univariate analysis showed that the incidence of incision infection was higher in patients with obesity (body mass index> 30 kg / m2), operation time exceeding 1 h, preoperative non-prophylactic use of antibiotics and dressing change> 3 d after initial incision (P < 0.05). Multivariate analysis showed that antibiotics administered for more than 1 h and preoperative prophylactic use were independent risk factors for incisional wound infection after acute suppurative perforated appendicitis (P <0.05). Conclusion Early diagnosis and treatment, reduce the operation time, preoperative prophylactic antibiotics can help reduce the chance of incision infection.