内镜注射疗法改善了消化性溃疡出血病人的预后,但最佳方案仍有待确定。本实验的目的是证明局部填塞能否有效地止血?肾上腺素是否引起动脉内膜炎和动脉栓塞?硬化剂能否制止急性溃疡出血并引起动脉内膜炎? 材料和方法新西兰白兔6只,禁食12小时,麻醉后作胃切开,按250 U/kg剂量将肝素注入耳静脉,用解剖刀及胃体胃窦处作6～8处的创口,切除直径为2.5～3.8 mm的园盘状粘膜组织。用事先称重的三角形吸湿纸吸附每一伤口的血液,根据出血多少,于30至60秒钟及5分钟后各再次称重,伤口总出血量每分钟超过1ml者作为研究对象。以随机的方法,用外径0.6 mm的23号Fr针头分别将1ml的生理盐水、1ml的1:1000,000ml肾上腺液或1ml的5%乙醇胺注入出血伤口之下,并立即测量60秒钟的失血量。其后处死动物,取胃作 Endoscopic injection therapy to improve the prognosis of patients with peptic ulcer bleeding, but the best program remains to be determined. The purpose of this experiment is to prove whether local packing can effectively stop bleeding? Epinephrine whether cause endarteritis and arterial embolism? Whether the hardening agent can stop the bleeding of acute ulcer and cause endarteritis? Materials and Methods New Zealand white rabbits 6, Fasting for 12 hours, after anesthesia for gastric incision, according to 250 U / kg dose of heparin into the ear vein with a scalpel and stomach gastric antrum for 6 to 8 wounds, removal of diameter 2.5 ~ 3.8 mm in the park Disk mucosal tissue. With the prior weighing of the triangular absorbent paper each wound blood, according to how much bleeding, 30 to 60 seconds and 5 minutes after each weighing again, the total amount of wound bleeding more than 1ml per minute as the object of study. In a randomized fashion, 1 ml of saline, 1 ml of 1: 1000,000 ml adrenal fluid, or 1 ml of 5% ethanolamine were each injected under a hemorrhagic wound with a No. 23 Fr needle having an outer diameter of 0.6 mm and immediately measured for 60 seconds Blood loss. Afterwards, the animals were sacrificed and the stomach was taken