肝纤维化为诸多慢性肝病发展至肝硬化过程中所共有的病理组织学变化 ,是影响慢性肝炎预后的重要环节。肝纤维化的治疗与慢性肝炎的总体治疗原则类同 ,包括病因的祛除 ,调控异常的免疫机能 ,抑制炎症反应、抗肝细胞损伤及坏死 ,减少细胞外基质 (ＥＣＭ )的增生与沉积 ,促进ＥＣ Liver fibrosis is a common pathological change in the development of many chronic liver diseases to cirrhosis and is an important part of the prognosis of chronic hepatitis. The treatment of liver fibrosis and the general principles of treatment of chronic hepatitis are the same, including the eradication of the etiology, regulating abnormal immune function, inhibiting inflammation, anti-hepatocyte injury and necrosis, reducing the extracellular matrix (ECM) proliferation and deposition, promote EC