0引言肿瘤是当今世界发病率及死亡率最高的疾病[1]。肿瘤发生发展是一个极为复杂的过程,流行病学资料显示,食物及其营养素从多方面影响着肿瘤的发生与发展[2-3]。硒(selenium,75Se)是一种具有抗癌效应的元素[4-7],它以无机亚硒酸盐或有机硒酸盐的形式存在于植物和其他有机食物中。人类硒基蛋白质组包含35种含硒蛋白质,它们具有广泛的生理功能。现将硒结合蛋白1(selenium binding protein-1,SBP1)在肿瘤中的作用综述如下。 0 Introduction Tumors are the most morbid and morbid diseases in the world today [1]. Tumor development is an extremely complicated process. Epidemiological data show that food and its nutrients influence the occurrence and development of tumors in many aspects [2-3]. Selenium (75Se) is an anti-cancer effect element [4-7], it is in the form of inorganic selenite or organic selenate in plants and other organic foods. The human selenoprotein group contains 35 selenium-containing proteins that have a wide range of physiological functions. The role of selenium binding protein-1 (SBP1) in tumors is summarized below.