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作者为评价恶性胶质瘤加速超分割放射治疗的疗效,对佛罗里达大学放射肿瘤学系1985年4月~1994年6月间的70例病理证实为恶性胶质瘤并适合作大剂量放疗之成人患者(75%为多形性成胶质细胞瘤,25%为星形细胞瘤)选作加速超分割放射治疗。均应用兆伏光子线束治疗,每天两次,每次1.5Gy,分次间隔至少6小时,靶区总剂量绝大多数为60Gy,4周完成治疗,其中58例为60Gy,3例为66Gy,6例为69Gy,1例为54Gy。2例固治疗未完成未列入分析。研究组68例,中位年龄52岁,中位
To evaluate the efficacy of accelerated hyper-fractionated radiotherapy for malignant gliomas, 70 patients with pathologically confirmed malignant gliomas from April 1985 to June 1994 at the University of Florida Department of Radiation Oncology, who were eligible for high-dose radiotherapy Patients (75% glioblastoma multiforme, 25% astrocytoma) were selected as accelerated hyperfractionated radiotherapy. All applications of megavoltage photon beam therapy, twice a day, each 1.5Gy, at least 6 hours intervals, the target dose of the vast majority of 60Gy, 4 weeks to complete the treatment, of which 58 cases of 60Gy, 3 cases of 66Gy, 6 cases of 69Gy, 1 case of 54Gy. 2 cases of solid treatment unfinished not included in the analysis. The study group of 68 patients, the median age of 52 years, the median