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1901年Prierre Curie成功地研制出放射性粒子,从而开始了组织间种植治疗肿瘤的时代。但由于当时释放出中高能γ射线,防护、质控、植入技术条件差,操作烦琐等因素,故临床应用发展非常缓慢。1979年开始报导~(125)I进入临床治疗脑肿瘤。80年代,由于低能γ射线放射性核素研制成功,以及计算机三维治疗计划系统和CT、MRI等扫描技术的应用,这种组织间近距离粒子治疗,明显提高了脑肿瘤局部控制率和延长了患者生存期,是一种新的治疗方法。90年代,特别是1998年中国原子能研究院解决了纳米焊接技术的难关,国产~(125)I放射微粒开始问世。以及和MRI、CT立体定向手术计划系统的完美结合,解决了放射性粒
In 1901 Prierre Curie successfully developed radioactive particles, which began the era of interstitial plant cancer treatment. However, due to the release of high-energy gamma rays, protection, quality control, poor implant conditions, cumbersome operation and other factors, the clinical application of the development is very slow. Beginning in 1979 reported ~ (125) I into clinical treatment of brain tumors. In the 1980s, due to the successful development of low-energy γ-ray radionuclides and the application of computerized three-dimensional treatment planning system and CT, MRI and other scanning techniques, this intra-tissue brachytherapy significantly improved the local control rate of brain tumors and prolonged the patients’ Survival, is a new treatment. In the 90s, especially China Institute of Atomic Energy in 1998 to solve the difficulties of nano-welding technology, domestic ~ (125) I emission particles began to come out. And MRI and CT stereotactic surgery planning system the perfect combination to solve the radioactive particles