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疾病是由于各种致病因素的综合致病力超过了人体免疫力，并达到发病阈值以上的结果。化学药品一般作用于疾病的某一发病环节，阻断病理过程，达到治疗疾病的目的。利用不同的药物作用于疾病的不同环节上，使综合致病力降低到疾病发病的阈值以下，使人体的免疫力足以对抗致病力时，疾病就能得以控制，达到治疗的目的。为了评价多种药物对疾病不同环节的综合作用，本文提出了用“水闸门”评价的一般方法，该方法把病理过程的各个阶段分为顺式途径和旁路途径两种，并初步提出了两个数学模型，以期说明用若干中等作用强度的药物对疾病各环节的阻断而达到的治疗效果，并不一定弱于那些对单靶点有高强度作用的药物的治疗作用。从而说明中药和中药复方中多种成分对疾病发病过程的不同环节或不同的靶点作用的综合性，解释中药或中药复方药效的科学内涵。
Disease is the result of the comprehensive virulence of various pathogenic factors that exceeds the human immune system and reaches above the morbidity threshold. Chemicals generally act on a certain pathological aspect of the disease, block the pathological process, and achieve the purpose of treating the disease. Use different drugs to act on different aspects of the disease to reduce the overall virulence to below the threshold of the disease, so that when the body’s immunity is sufficient to fight virulence, the disease can be controlled to achieve the purpose of treatment. In order to evaluate the comprehensive effects of various drugs on different aspects of the disease, this article proposes a general method for the evaluation of “sluice gates”. This method divides the stages of the pathological process into two types: the cis-pathway and the bypass pathway. Two mathematical models that attempt to illustrate the therapeutic effect achieved by the blockage of several intermediate-strength-strength drugs on various aspects of the disease are not necessarily weaker than those of drugs that have a high-intensity effect on single targets. Thus, it can explain the comprehensiveness of the effects of various components of traditional Chinese medicine and traditional Chinese medicine on different stages or targets of the disease, and explain the scientific connotation of the efficacy of traditional Chinese medicine or traditional Chinese medicine compound.