动脉导管未闭(PDA)是影响早产儿死亡率和致残率的重要因素之一。胎龄和体重越小,发病率越高[1]。早产儿动脉导管管壁薄,缺乏肌肉组织,对氧等刺激收缩的因素敏感性低,对前列腺素等松弛平滑肌的因素敏感性高。一、早产儿PDA的临床表现和诊断PDA早产儿在早期无症状,随着新生儿肺部 Patent ductus arteriosus (PDA) is one of the important factors affecting the mortality and morbidity of premature infants. The smaller the gestational age and weight, the higher the incidence [1]. Arterial catheters in preterm infants have a thin wall and a lack of muscle tissue and are less sensitive to factors such as oxygen to stimulate contractions and to factors that relax smooth muscle such as prostaglandins. First, the clinical manifestations and diagnosis of PDA in premature children PDA premature children asymptomatic in the early, with the newborn lung