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目的优选天杞颗粒的最佳制备工艺。方法以多糖为指标,正交实验法优选水提条件;以颗粒吸湿性和成型性为指标,筛选颗粒最佳辅料与配比。结果最佳水提工艺为药材加10倍量水,煎煮3次,每次1.5 h;制备天杞颗粒的最优处方组成为:干膏∶糊精∶阿斯巴甜1∶4∶0.04,95%乙醇混匀制粒。结论该制备工艺科学合理,简便实用。
Objective To optimize the preparation of Tianqi granules. Methods polysaccharide as an indicator, orthogonal experimental optimization of water extraction conditions; particle moisture absorption and formability as an indicator, the best particle screening materials and the ratio. Results The best water extraction process for the herbs plus 10 times the amount of water, boiling three times, each 1.5 h; preparation of the optimal prescription Tianqi granules composition: dry paste: dextrin: aspartame 1: 4:0.04 , 95% ethanol mixing granulation. Conclusion The preparation process is scientific and reasonable, simple and practical.