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本文对２７例染色体异常患者的孕产史进行分析发现：２１例平衡易位携带者共流产５８胎次，平均每例流产近３次，２１例患者共孕产８１胎次，生育表型正常儿１２胎次，机率为２．６６：１８，稍高于理论值，其中男性患者生育表型正常儿机率为２５％，比女性患者高１２．７个百分点。臂间倒位患者子代胚胎的正常与否，与臂间倒位片段的长短有关，片段越长，胚胎成活率越高。总之，对所有有生育能力的染色体异常患者仍应做产前诊断，同时加强家系调查，提高异常检出率，控制不良遗传因素个体的出生，以此达到优生目的。
In this paper, 27 cases of chromosomal abnormalities in the history of pregnant women were analyzed: 21 cases of balanced translocation carrier cohabitation 58 warts, the average of each abortion nearly 3 times, 21 patients were pregnant with a total of 81 births, fertility phenotype 12 twins, a probability of 2.66: 18, slightly higher than the theoretical value, of which male patients with normal phenotype of child birth rate of 25%, 12.7 percentage points higher than the female patients. Arrhythmia in the offspring of offspring embryos normal or not, and the length of the arm internals segment, the longer the fragment, the higher the survival rate of embryos. In short, all fertile chromosomal abnormalities should still be done prenatal diagnosis, while strengthening the pedigree investigation to improve the anomaly detection rate, control the birth of individuals with poor genetic factors, in order to achieve the purpose of eugenics.