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先天性肥厚性幽门狭窄(Congenital Hypertrophic Pyloric Stenosis,CHPS)是新生儿常见的消化道畸形,发病率在国外较高,达1.5‰～4.0‰,国内稍低,为0.3‰～1.0‰,均为足月婴幼儿,头胎多见,男性占80%,男女发病率比例约为4～8∶1[1]。CHPS是由于新生儿幽门肌层(尤其是环形肌)过度增生、肥厚导致幽门管狭窄的上消化道梗阻性疾病,症状多于出生2周后出现,临床主要表现为呕吐、胃蠕动波、右上腹包块三大症状。如不早期诊断及治疗,后期患儿常因严重营养不良而衰竭死亡,故早期诊断、及时治疗对患者有积极意义。
Congenital Hypertrophic Pyloric Stenosis (CHPS) is a common neonatal gastrointestinal malformations, the incidence of higher in foreign countries, up to 1.5 ‰ ~ 4.0 ‰, slightly lower in China, 0.3 ‰ ~ 1.0 ‰, were Full-term infants and young children, more common first-born, male 80%, the incidence of men and women is about 4 ~ 8: 1 [1]. CHPS is due to neonatal pyloric muscle layer (especially the ring muscle) hyperplasia, hypertrophy caused by upper gastrointestinal obstruction of pyloric stenosis, the symptoms occur more than 2 weeks after birth, the main clinical manifestations of vomiting, gastric motility wave, the upper right Abdominal mass three symptoms. If not early diagnosis and treatment, the latter often due to severe malnutrition and death failure, so early diagnosis and timely treatment of patients with positive significance.