吉毗隆（gepirone，BMY－13805）是一种5－HT；。受体激动剂，与丁螺环酮结构类似，目前已广泛用于抗焦虑症；临床前和临床研究表明，它们均具有抗焦虑作用，目前研究提示，吉毗隆治疗抑郁症更有用。吉毗隆的代谢与丁螺环酮相似，首先代谢为羟化衍生物，再氧化断裂为生物活性代 Gepirone (BMY-13805) is a 5-HT ;. Receptor agonists, similar in structure to buspirone, are now widely used in the treatment of anxiety disorders; preclinical and clinical studies have shown that they all have anxiolytic effects and current research suggests that it is more useful for treating depression. Gemcitabine metabolism is similar to buspirone, which is first metabolized to a hydroxylated derivative and then oxidized to a bioactive