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目的:调查局限期膀胱癌患者术后膀胱灌注化疗的依从性,分析其影响因素。方法:选取局限期膀胱癌术后患者260例,随访2年观察其依从性,统计依从性较差患者的影响因素。结果:所有患者均获得随访,随访时间(1.9±0.1)年,6.15%患者于随访期间死亡。女性患者依从性低于男性患者,≥60y患者依从性低于<60y患者,≤初中文化程度患者依从性低于≥高中文化程度患者,自费患者依从性低于第三方付费患者,健康教育效果欠佳患者依从性低于健康教育效果良好患者,随着病理分期的增加,患者依从性逐渐降低,上述差异均具有统计学意义。91.30%的依从性较差的患者给予了未遵医嘱化疗的原因,不良反应、经济负担、对疾病知识缺乏正确认识等是影响依从性的主要原因。结论:局限期膀胱癌患者术后膀胱灌注化疗的依从性较差,性别、高龄、文化程度、医疗费用支付方式、经济承受能力、健康教育效果、疾病严重程度等均为影响依从性的重要因素,建议予以个体化的护理干预。
OBJECTIVE: To investigate the compliance of postoperative bladder irrigation chemotherapy in patients with locally advanced bladder cancer and to analyze the influencing factors. Methods: Two hundred and six patients with localized bladder cancer were selected and followed up for 2 years to observe the compliance and the influencing factors of poor compliance. RESULTS: All patients were followed up for a mean follow-up of 1.9 ± 0.1 years and 6.15% died during follow-up. Female patients compliance less than male patients, ≥ 60y patients compliance less than <60y patients, ≤ junior high school education in patients with less than or equal to high school education, patients with self-pay less compliance than third-party paid patients, health education effect Good patient compliance is lower than that of health education patients with good results, with the increase of pathological stage, patient compliance decreased gradually, the above differences were statistically significant. 91.30% of the patients with poor compliance were given the reasons for the failure to follow the instructions of chemotherapy, adverse reactions, economic burden, the lack of a correct understanding of the disease knowledge is the main reason for compliance. CONCLUSIONS: The bladder cancer patients with definite stage of bladder cancer have poor compliance after operation, and sex, age, educational level, payment of medical expenses, affordability, health education effect, disease severity and so on are the important factors that affect the compliance , It is recommended to be individualized nursing intervention.