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对４２例急性一氧化碳（ＣＯ）中毒患者动脉血气深部图象的变化及影响因素进行研究，结果显示：１．碳氧血红蛋白（ＣＯＨｂ）浓度升高，与临床症状大致相关，一般ＣＯＨｂ＞３０％出现昏迷，＞４０％出现心肺脑严重并发症，但各组间存在较大重叠。２．血氧含量（ｃｔＯ２）反映血液向组织供氧能力，是代表心、肺功能和代谢状态三方面综合性因素的参数，在这类患者中均下降，其下降程度较ＣＯＨｂ升高程度与病情轻重更相关。３．血氧饱和度为５０％时的氧分压（Ｐ（５０）Ｏ２）在轻、中症患者中下降，表明存在氧解离曲线左移，Ｏ２Ｈｂ在组织水平不易与Ｏ２分离，部分重症患者Ｐ（５０）Ｏ２值正常或升高，可能与同时存在着严重代谢性酸中毒有关。我们认为深部图象能使ＣＯ中毒时诊断迅速、准确，对组织供氧状况进行全面评估，因而具有重要临床价值。对深部图象的研究结果提示对急性ＣＯ中毒患者，低流量吸Ｏ２对改善组织缺Ｏ２无重要意义。我们认为当ＣＯＨｂ＞１５％时应吸入高浓度（１００％）氧，ｃｔＯ２＜１２ｖｏｌ％应行高压氧治疗，对代谢性酸中毒的患者的治疗原则ｐＨ＜７．２５以下可给半量补碱。
In 42 cases of acute carbon monoxide (CO) poisoning in patients with arterial blood gas changes in the depth of the image and the impact of factors, the results showed that: 1. The concentration of carboxyhemoglobin (COHb) increased, which was generally associated with clinical symptoms. Coma was found in> 30% of patients with COHb, and severe cardiopulmonary and cerebrovascular complications> 40%. However, there was a large overlap between the two groups. 2. Blood oxygen content (ctO2) reflects the ability of blood to supply oxygen to the tissues. It is a parameter that represents the comprehensive factors of heart, lung function and metabolic status. The blood oxygen content (ctO2) is decreased in all the patients. The degree of decline is more serious than that of COHb More relevant. 3. Oxygen partial pressure (P (50) O2) at 50% oxygen saturation decreased in patients with mild to moderate disease, indicating the presence of oxygen dissociation curve to the left, O2Hb at the tissue level is not easy to separate with O2, some patients with severe P (50) Normal or elevated O2 values may be related to the presence of severe metabolic acidosis. We believe that deep images can make the diagnosis of CO poisoning rapid and accurate, a comprehensive assessment of tissue oxygen status, which has important clinical value. The results of the deep image suggest that in patients with acute CO poisoning, low-flow O2 extraction is not important in improving tissue hypoxia. We believe that when COHb> 15% inhalation of high concentrations (100%) of oxygen, ctO2 <12vol% should be hyperbaric oxygen therapy, metabolic acidosis in patients with the principle of treatment pH <7.25 can give half the amount of base.