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目的 探讨放射性核素骨显像及人类白细胞抗原 (HLA B2 7)检查对强直性脊椎炎 (AS)早期诊断价值。方法 对首次发病且X线检查未见异常的 35例后臀部疼痛患者作了骨显像及HLA B2 7测定 ,并制订了对AS的早期诊断标准 ,对患者临床随访 0 5～ 2 5a ,用纽约会议标准再次进行诊断 ,以评价早期诊断标准的准确性。结果 根据早期诊断标准有 30例患者被诊断为AS ,随访后再次诊断 ,其中 2 9例被诊断为AS ,前后 2次诊断符合率为 96 7%。结论 放射性核素骨显像与HLA B2 7检查相结合对AS的早期诊断和治疗可提供可靠依据。
Objective To investigate the diagnostic value of radionuclide bone imaging and human leukocyte antigen (HLA B2 7) in the early diagnosis of ankylosing spondylitis (AS). Methods 35 patients with posterior hysterical pain who had no initial abnormality and X-ray examination were examined with bone imaging and HLA B2 7, and the early diagnosis criteria of AS were established. The clinical follow-up of patients with 0.5 to 2.5 years was performed with The New York Conference Standards are once again diagnosed to assess the accuracy of early diagnostic criteria. Results According to the criteria of early diagnosis, 30 patients were diagnosed as AS and were diagnosed again after follow-up. Among them, 29 patients were diagnosed as AS with a coincidence rate of 96.7% before and after diagnosis. Conclusion The combination of radionuclide bone imaging and HLA B2 7 examination can provide a reliable basis for the early diagnosis and treatment of AS.