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短串联重复序列(STR),是由几个碱基对作为核心单位,串联重复形成的一类DNA序列。由于其核心重复单位数目的变化构成了STR基因座的遗传多态性。在人类基因组中,平均每15kb就存有1个STR基因座,为法医个人识别和亲子鉴定提供了高信息基因座的丰富来源。1991年,Edwards[1]
Short tandem repeats (STRs) are a series of DNA sequences that are repeatedly formed in tandem by a few base pairs as the core unit. Due to changes in the number of its core repeat units constitute the STR locus genetic polymorphism. In the human genome an average of one STR locus per 15kb provides a rich source of high-informative loci for forensic and paternity testing. In 1991, Edwards [1]