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目的观察分析鼻塞持续气道正压通气(NCPAP)与珂立苏联用治疗新生儿肺透明膜病的临床疗效。方法 60例新生儿肺透明膜病患儿,随机分为观察组和对照组,每组30例。观察组采用NCPAP与珂立苏联用进行治疗,对照组采用NCPAP进行治疗,比较两组治疗效果。结果观察组总有效率93.3%与对照组73.3%相比,差异有统计学意义(χ2=4.32,P<0.05);治疗后,观察组动脉血氧分压(Pa O2)、二氧化碳分压(Pa CO2)与对照组相比明显改善,差异有统计学意义(P<0.05);两组并发症总发生率相比,差异有统计学意义(χ2=5.08,P<0.05)。结论采用NCPAP治疗新生儿肺透明膜病,临床疗效较好,治愈率较高,能够明显改善患儿的新生儿肺透明膜病的症状,提高患儿的存活率,具有临床应用推广价值。
Objective To observe and analyze the clinical efficacy of nasal continuous positive airway pressure (NCPAP) combined with coriolis in the treatment of neonatal hyaline membrane disease. Methods Sixty newborns with hyaline membrane disease were randomly divided into observation group and control group with 30 cases in each group. The observation group was treated with NCPAP and Ke Li Su, while the control group was treated with NCPAP. The therapeutic effect was compared between the two groups. Results The total effective rate of observation group was 93.3% compared with 73.3% of control group (χ2 = 4.32, P <0.05). After treatment, PaO2 and CO2 partial pressure (P <0.05). There was significant difference between the two groups in total incidence of complications (χ2 = 5.08, P <0.05). Conclusion NCPAP treatment of neonatal hyaline membrane disease has good clinical curative effect and high cure rate, which can significantly improve the symptoms of neonatal hyaline membrane disease and improve the survival rate of children with clinical application.