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低氧诱导因子(HIF)是恶性肿瘤适应低氧微环境的关键因子,已成为恶性肿瘤抑制剂及基因治疗研究的重要靶点,本文综述其在肿瘤抑制剂治疗中的研究进展。
Hypoxia-inducible factor (HIF) is a key factor for malignant tumor to adapt to hypoxia microenvironment and has become an important target of malignant tumor suppressor and gene therapy research. This article reviews its research progress in the treatment of tumor suppressor.