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竞争性组胺 H_2-受体拮抗剂西咪替丁广泛应用于治疗和预防人的胃肠道溃疡和减少胃酸过多。它有极性和亲水性质,限制了它对生物膜的穿透作用。日服后生物利用度约为70%。
Competitive histamine H 2 -receptor antagonist cimetidine is widely used in the treatment and prevention of gastrointestinal ulcers in humans and reduces hyperacidity. It has polar and hydrophilic properties, limiting its penetration into biofilms. After serving on the bioavailability of about 70%.