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目的探讨急性心肌梗死(AMI)患者应用血清C-反应蛋白(CRP)、肌钙蛋白I(c Tn I)联合检测的诊断效果。方法选取2013年5月至2015年7月AMI患者65例为AMI组,选取同期普通冠心病患者65例为冠心病组,选取同期体检健康者65例为健康组,记录比较三组血清CRP、c Tn I水平,比较AMI组血清CRP、c Tn I单项检测与联合检测的阳性率。结果 AMI组血清CRP、c Tn I水平均高于冠心病组和健康组(P<0.05);冠心病组血清CRP、c Tn I水平均高于健康组(P<0.05);AMI组血清CRP、c Tn I及联合检测阳性率依次为86.15%、26.15%及96.92%,联合检测阳性率均明显高于单项检测(P<0.05)。结论急性心肌梗死患者采用血清CRP、c Tn I联合检测能显著提高诊断率,临床应用价值较高。
Objective To investigate the diagnostic value of combined detection of serum C-reactive protein (CRP) and troponin I (cTn I) in patients with acute myocardial infarction (AMI). Methods 65 patients with AMI from May 2013 to July 2015 were selected as the AMI group. Sixty-five patients with coronary heart disease in the same period were selected as coronary heart disease group. Sixty-five healthy subjects were selected as healthy group. Serum levels of CRP, cTn I levels, the level of serum CRP, c Tn I single test and combined detection of positive rate in AMI group were compared. Results Serum levels of CRP and cTnI in AMI group were significantly higher than those in CHD group and healthy group (P <0.05). Serum levels of CRP and cTnI in AMI group were significantly higher than those in healthy group (P <0.05) The positive rates of cTn I and combined tests were 86.15%, 26.15% and 96.92%, respectively. The positive rates of combined detection were significantly higher than those of single detection (P <0.05). Conclusions The combined detection of serum CRP and cTnI in patients with acute myocardial infarction can significantly improve the diagnostic rate and have a high clinical value.