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目的:探讨腭裂术后语音障碍患者声门塞音对鼻音计评价腭咽闭合状态的影响。方法:纳入2004年8月至2010年8月北京大学口腔医学院·口腔医院口腔颌面外科收治的71例腭裂术后语音障碍患者,腭裂代偿语音评价为伴或不伴声门塞音,男性50例,女性21例,年龄(15.9±6.2)岁。应用鼻音计和鼻咽纤维内镜同步检查,记录所有患者鼻音计鼻音化率值和鼻咽纤维内镜视觉模拟量表(visual analog scale,VAS)分值数据,并根据声门塞音语音评价结果将患者分成3组,即整体组(未排除声门塞音)、声门塞音组及无声门塞音组,对3组患者的11个语音样本(单元音1~3号、连续音节4~9号、语句10~11号)鼻音化率值与VAS值进行Pearson相关分析。结果:整体组患者71例,声门塞音组患者34例,无声门塞音组37例。整体组患者的11个语音样本鼻音化率值与VAS值间均呈负相关趋势,但均无显著的相关关系(n r>-0.179且0.05);声门塞音组各语音样本鼻音化率值与VAS值之间均无显著的相关关系(n r>-0.196且0.05);无声门塞音组除1、3、11号语音样本外,其余各语音样本鼻音化率值与VAS值均呈显著负相关关系(n r>-0.557且-0.196 and0.05). There was a significant negative correlation between nasal phonetic rate and VAS value of all but No. 1, 3 and 11 speech samples in silent door plug group (n P<0.05), among which No. 7 speech sample was the most sensitive sample (n r=-0.557, n P<0.05).n Conclusions:The present study showed the glottal stops could affect the evaluation of the velopharyngeal closure function by using nasometer. Glottal stops should be considered as one important factor for the nasalance.