高血压所致的亚临床血管病变主要包括血管内皮功能障碍,动脉内中膜厚度增加、斑块形成,大动脉弹性降低、僵硬度增加等。判断大动脉弹性及僵硬度可以通过脉压、脉搏波形分析、脉搏波速度、组织多普勒成像等。早期检测亚临床血管病变,可发现高危人群,早期治疗,逆转或延缓亚临床病变,避免发展到明显靶器官损害甚至临床相关疾病。 Subclinical vascular disease caused by hypertension mainly includes vascular endothelial dysfunction, increased intima-media thickness, plaque formation, reduced aortic elasticity and increased stiffness. Judgment of aortic elasticity and stiffness can be by pulse pressure, pulse wave analysis, pulse wave velocity, tissue Doppler imaging. Early detection of subclinical vascular lesions can be found in high-risk groups, early treatment, reverse or delay subclinical lesions, to avoid the development of obvious target organ damage and even clinically related diseases.