中毒性休克综合征(Toxic shock syn-drome,简称 TSS)是一种新认识的严重临床病症,以发热、晕厥、低血压或休克、粘膜弥漫性炎症、恶心、呕吐、腹泻及多脏器系统功能障碍等为特征:早期报道的 TSS 病例主要见于育龄妇女,多与行经期使用受金黄色葡萄球菌(下称金葡菌)污染的月经塞有关。近年来,对 TSS 的发病机理,金葡菌及其致热性外毒素的作用等方面进行了较深入的研究,为系统认识本病打下了基础。本文就其最近进展情况作一综述。 Toxic shock syn-drome (TSS) is a newly recognized serious clinical condition characterized by fever, syncope, hypotension or shock, mucosal diffuse inflammation, nausea, vomiting, diarrhea and multiple organ systems Dysfunction, etc. are characterized by: Early reports of TSS cases are mainly seen in women of childbearing age, and more use of menstrual corks contaminated with Staphylococcus aureus (Staphylococcus aureus) during menstruation. In recent years, the pathogenesis of TSS, the role of Staphylococcus aureus and its pyrogenic exotoxin have been studied in depth, which laid the foundation for systematic understanding of the disease. This article reviews recent progress.