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[目的]探讨两种综合治疗方法治疗支气管结核(EBTB)的临床治疗效果。[方法]收集2006年9月~2009年12月于我院确诊的EBTB患者83例,按随机原则分为对照组42例及治疗组41例,对照组采用3HREZ/9HRE方案全身抗结核化疗+雾化吸入抗结核药物治疗;治疗组在对照组的基础上应用电子支气管镜局部给药治疗。[结果]治疗组在治疗3个月、1年以及停药随访1年后胸部X/CT线总体有效率、支气管镜冲洗液抗酸杆菌集菌转阴率及支气管镜镜下改变总体有效率3项指标均明显由于对照组,两组比较差异均有统计学意义(P﹤0.05)。[结论]在全身化疗+雾化的基础上应用支气管镜局部给药治疗EBTB疗效显著,可促进病灶的吸收、抗酸杆茵阴转及有效地防止支气管狭窄,提高EBTB的治愈率。
[Objective] To explore the clinical effects of two kinds of comprehensive treatment for bronchial tuberculosis (EBTB). [Methods] Eighty-three patients with EBTB diagnosed in our hospital from September 2006 to December 2009 were divided into control group (n = 42) and treatment group (n = 41) according to the randomized principle. The control group was treated with 3HREZ / 9HRE systemic anti-TB chemotherapy + Attenuated inhalation of anti-TB drugs; treatment group in the control group based on the application of electronic bronchoscopy local administration. [Results] The total effective rate of chest X / CT line, the acid-fast bacilli-negative rate of bronchoscope irrigating fluid and the total effective rate of bronchoscopy under 3 months, 1 year and 1 year follow-up after treatment in the treatment group were significantly lower All three indicators were significantly different in the control group and the two groups were statistically significant (P <0.05). [Conclusion] The application of topical bronchoscopical bronchoscopy to treat EBTB on the basis of systemic chemotherapy and nebulization has significant curative effect, which can promote the absorption of the lesion, resist the acid and cure the Yin Yin and prevent the bronchoconstriction and improve the cure rate of EBTB.