大鼠胚胎海马移植物治疗~(137)Csγ射线所致的脑机能障碍

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用条件饮水反应实验方法检测大鼠的学习能力。应用外科手术将大鼠胚胎海马组织移植物植人35日龄受照大鼠海马。结果表明,大鼠条件饮水测验成绩具有波动性;手术前后对照大鼠条件饮水测验成绩无显著差异(p>0.05),而移植组大鼠手术后的条件饮水测验成绩显著高于手术前(p<0.01);手术前两组大鼠的条件饮水测验成绩无显著差异(P>0.05),手术后移植组大鼠条件饮水测验成绩显著高于对照组(P<0.01)。这提示移植手术确实能治疗大鼠出生前137CSγ射线照射所致的脑机能障碍。 Conditioned drinking water response test was used to test the learning ability of rats. The hippocampus of 35-day-old rats was implanted with rat embryo hippocampus by surgical operation. The results showed that the results of the conditioned drinking water test in rats were volatile. There was no significant difference in the conditioned drinking water test scores between before and after surgery (p> 0.05), while the experimental drinking water test scores of the rats in the transplantation group were significantly higher than those before operation (P <0.01). There was no significant difference in the conditioned drinking water test scores between the two groups before surgery (P> 0.05). The results of conditioned drinking water test in the transplantation group were significantly higher than those in the control group (P <0.01). 01). This suggests that transplants do indeed treat brain dysfunction caused by 137CS gamma irradiation prior to birth in rats.
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