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目的观察丙泊酚在人工流产中静脉给药的镇痛作用。方法自愿进行人工流产术患者,无禁忌证孕5~10周妇女168例作为研究对象,将其随机分为用药组和对照组。用药组126例,术前给予丙泊酚2.0 mg/kg静脉注射,如手术时间超过8 min,追加药量50~70 mg;对照组42例,不使用任何镇痛药。结果用药组126例患者镇痛效果总有效率100%,均未出现人工流产综合反应,对照组总有效率为32%,两组比较差异有统计学意义(P<0.01)。结论丙泊酚用于人工流产术镇痛效果显著,安全可靠,值得推广应用。
Objective To observe the analgesic effect of propofol intravenously in induced abortion. Methods A total of 168 women who had contraindications of 5 to 10 weeks before pregnancy were enrolled in this study. They were randomly divided into medication group and control group. In the treatment group, 126 cases were given propofol 2.0 mg / kg intravenously before surgery. For example, the operation time exceeded 8 minutes and the additional dose was 50-70 mg. In the control group, 42 cases were given no analgesics. Results The total effective rate of analgesic effect of the 126 patients in the medication group was 100%. No artificial abortion combined reaction was found. The total effective rate of the control group was 32%. There was significant difference between the two groups (P <0.01). Conclusion Propofol analgesic effect of artificial abortion is significant, safe and reliable, it is worth to promote the application.