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用氧氟沙星加氨苄青霉素治疗伤寒26例,并以单用氨苄青霉素的对照组20例对比。前者退热天数为3.88±2.34天5后者为9.75±4.42天(P<0.05);前5者有效率100%,后者有效率45%(P<0.0001);前者复发率0,后者复发率15%(P<0.000013)。认为氧氟沙星加氨苄青霉素治疗伤寒疗效高,抗复发性强,可作为伤寒的首选药物之一。
Ofloxacin plus ampicillin in the treatment of typhoid fever in 26 cases, and single control group with ampicillin in 20 cases. The former was 3.88 ± 2.34 days and the latter was 9.75 ± 4.42 days (P <0.05). The first five were 100% effective and the latter 45% effective (P < 0.0001). The former had a recurrence rate of 0 and the latter had a recurrence rate of 15% (P <0.000013). That of ofloxacin plus ampicillin treatment of typhoid fever, anti-recurrent strong, can be used as one of the first choice of typhoid fever.