由美国科学家完成的一项关键研究发现,参与催化反应的酶经过详细的构象变化,从而完成其生物学功能,该发现向传统药物合成途径的假想提出了挑战,并可能帮助未来的药物设计。传统认为,酶是主要以其生命存在来催化化学反应的生物学分子,酶催化作用传统模式将被这些发现重写,另外, A key study by US scientists found that enzymes involved in catalytic reactions undergo a detailed conformational change that completes their biological function, a finding that challenges the hypotheses of traditional drug-synthesis pathways and may help future drug design. Traditionally, enzymes are the biological molecules that mainly catalyze chemical reactions by their existence. The traditional model of enzymatic catalysis will be rewritten by these findings. In addition,