27例糖尿病酮症酸中毒和高渗昏迷的临床资料分析表明,多脏器功能衰竭(MOF)多见于Ⅱ型糖尿病患者,有随年龄增加而增加的趋势。酮症酸中毒合并MOF的机率低于高渗昏迷。MOF发生的主要诱因为感染和停药,血糖升高为重要的促发因素。影响预后的因素复杂,血压下降为一重要死因,糖尿病本身正规治疗,及早抗感染和监测血糖,血压对减少其发生率和病死率至关重要,在老年病人尤甚。 27 cases of diabetic ketoacidosis and hyperosmolar coma clinical data analysis showed that multiple organ failure (MPF) more common in patients with type 2 diabetes, with the increasing trend of age. Ketoacidosis combined MOF less likely than hypertonic coma. The main causes of MOF infection and withdrawal, elevated blood glucose is an important contributing factor. The factors that influence the prognosis are complex, and the decline in blood pressure is a significant cause of death. The regular treatment of diabetes itself, early anti-infectives and monitoring of blood glucose, and blood pressure are crucial for reducing their incidence and mortality, especially in the elderly.