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目的测定慢性前列腺炎患者前列腺特异性抗原（ＰＳＡ）在前列腺液中的变化，以探讨其对此类疾病诊断的意义。方法对５５例慢性前列腺炎及１１例泌尿外科非前列腺炎疾病患者的前列腺液进行常规检查、细菌培养和ＰＳＡ光密度值（ＯＤ值）检测。结果实验组的ＰＳＡ水平较对照组明显升高（Ｐ＜０．０１），而在细菌性及非细菌性前列腺炎时ＰＳＡ水平无明显变化，实验组与对照组卵磷脂小体差异有极显著性（Ｐ＜０．０００５），实验组前列腺液中的白细胞计数与ＰＳＡ相关系数ｒ＝０．２，Ｐ＜０．０４。结论慢性前列腺炎时前列腺液中的ＰＳＡ可增高，ＰＳＡ可作为诊断慢性前列腺炎的一个辅助指标。
Objective To determine the changes of prostatic specific antigen (PSA) in prostatic fluid in patients with chronic prostatitis to explore its significance in the diagnosis of such diseases. Methods Prostate fluid from 55 patients with chronic prostatitis and 11 patients with non-prostatitis urological diseases were routinely examined, cultured in bacteria and examined for OD value of PSA. Results The level of PSA in the experimental group was significantly higher than that in the control group (P <0.01), while there was no significant difference in the PSA level between the bacterial and nonbacterial prostatitis group. The difference between the experimental and control groups was significant (P <0.0005). The correlation coefficient between white blood cell count and PSA in experimental group was 0.2, P <0.04. Conclusions PSA in prostatic fluid may be increased in patients with chronic prostatitis, and PSA may be used as an adjunct to diagnosis of chronic prostatitis.