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所谓脑代谢激活剂可认为就是在各种原因使脑代谢障碍时,能促进脑的功能、改善临床症状的药物的总称.如ATP及与脑代谢过程相联系的各种酶、辅酶、维生素、中间代谢产物等在实验与临床中都有改善脑代谢异常的作用.另一方面在脑血管障碍时,与激活脑代谢相反的,还有脑代谢抑制剂,如低温疗法及氯丙嗪,近年来引人注目的是巴比妥类对脑缺氧有保护脑的作用.这两个互相矛盾的疗法,尽管作用机制不相同,但在最终都是致使脑代谢改善这一点上是相同的.脑缺血与脑代谢正常人的脑接受心输出量15%的血液,其氧耗量相当于全身的20%,葡萄糖
The so-called brain metabolic activators can be considered in various causes of cerebral metabolic disorders, can promote brain function, improve clinical symptoms of drugs in general, such as ATP and the brain metabolic processes associated with various enzymes, coenzymes, vitamins, Intermediate metabolites and other experiments and clinics have improved the role of cerebral metabolic abnormalities on the other hand in the cerebrovascular disorders, and activate the brain metabolism in the opposite, as well as cerebral metabolic inhibitors, such as hypothermia and chlorpromazine in recent years It is striking that the barbiturates protect the brain from hypoxia, and the two conflicting treatments, albeit with different mechanisms of action, are the same in the end that all lead to an improvement in brain metabolism. Cerebral Ischemia and Brain Metabolism Normal human brain receives 15% of cardiac output of blood, its oxygen consumption is equivalent to 20% of the whole body, glucose