动脉粥样硬化(AS)是心脑血管疾病的主要病理基础,近年来国内外对抗AS药物的研究进展很快,笔者根据我国的应用情况,对有关文献综述如下:1 调血脂性抗动脉粥样硬化药1·1 胆汁酸鳌合剂 这类药物又称胆汁酸结合树酯,口服在胃肠道不被吸收,在肠道与胆汁酸鳌合,阻断胆汁酸的肝肠循环,使胆固醇(ch)在肝细胞内转化为胆汁酸,导致血 Atherosclerosis (AS) is the main pathological basis of cardiovascular and cerebrovascular diseases. In recent years, the research on anti-AS drugs at home and abroad has progressed rapidly. According to the application of our country, the author summarized the relevant literature as follows: 1, Like sclerosis medicine 1.1 bile acid chelator These drugs, also known as bile acid binding resin, oral absorption in the gastrointestinal tract is not, in the intestine and bile acid chelation, blocking the bile acid enterohepatic circulation, cholesterol ( ch) is converted to bile acid in liver cells, resulting in blood