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本文报道了22例,年龄小于70岁的急性脑梗塞患者(颈内动脉系统)分2组,分别采用小剂量尿激酶静脉注射及采用脉络宁加刺五加注射液为对照,观察14天发现尿激酶治疗组疗效启动快,用药后24小时内神经系统功能恢复明显加快,使病程明显缩短且副作用少,总显效率达81%,用药后24小时内体征恢复与48小时比较,存在显著性差异X2=4.36,P<0.05。而对照组疗效差,总显效率达18.1%。结果尿激酶组神经功能恢复明显优于对照组。由于脑血管的特点加之梗塞后病理改变,易发生出血危险,但只要病例选择适当,注意观察,用小剂量尿激酶静脉注射仍不失为治疗急性脑梗塞较好手段之一。
This article reports 22 cases of patients with acute cerebral infarction less than 70 years old (internal carotid artery system) were divided into 2 groups, respectively, by intravenous injection of low-dose urokinase and Mailuoning plus acanthopanax injection as control, observed 14 days found Urokinase treatment group started fast, within 24 hours after treatment, the nervous system recovery was significantly accelerated, the course of the disease was significantly shortened with fewer side effects, the total effective rate was 81%, within 24 hours after treatment signs recovered 48 hours, there was significant Difference X2 = 4.36, P <0.05. The poor efficacy of the control group, the total effective rate of 18.1%. Results Urokinase group had better neurological function than control group. Due to the characteristics of cerebrovascular and pathological changes after infarction, prone to bleeding risk, but as long as the appropriate choice of cases, pay attention to observation, intravenous injection of low-dose urokinase is still one of the better means of treatment of acute cerebral infarction.